medchemexpress nucleoside library Search Results


93
MedChemExpress medchemexpress nucleoside library
Medchemexpress Nucleoside Library, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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86
MedChemExpress nucleotide compound library
Principle of the 2-aminopurine exonuclease assay. (A) Schematic representation of a DNA substrate containing a 2-AP <t>nucleotide</t> positioned at the 3’ end, where its fluorescence is quenched by the neighbouring bases. Upon cleavage by an exonuclease, the 2-AP is released from the DNA and its fluorescence restored. (B) Comparison of the chemical structures of adenine, guanine, and 2-aminopurine.
Nucleotide Compound Library, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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99
MedChemExpress gpcr g protein compound library
Principle of the 2-aminopurine exonuclease assay. (A) Schematic representation of a DNA substrate containing a 2-AP <t>nucleotide</t> positioned at the 3’ end, where its fluorescence is quenched by the neighbouring bases. Upon cleavage by an exonuclease, the 2-AP is released from the DNA and its fluorescence restored. (B) Comparison of the chemical structures of adenine, guanine, and 2-aminopurine.
Gpcr G Protein Compound Library, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Principle of the 2-aminopurine exonuclease assay. (A) Schematic representation of a DNA substrate containing a 2-AP nucleotide positioned at the 3’ end, where its fluorescence is quenched by the neighbouring bases. Upon cleavage by an exonuclease, the 2-AP is released from the DNA and its fluorescence restored. (B) Comparison of the chemical structures of adenine, guanine, and 2-aminopurine.

Journal: bioRxiv

Article Title: A high-throughput exonuclease assay based on the fluorescent base analog 2-aminopurine

doi: 10.1101/2022.09.12.507544

Figure Lengend Snippet: Principle of the 2-aminopurine exonuclease assay. (A) Schematic representation of a DNA substrate containing a 2-AP nucleotide positioned at the 3’ end, where its fluorescence is quenched by the neighbouring bases. Upon cleavage by an exonuclease, the 2-AP is released from the DNA and its fluorescence restored. (B) Comparison of the chemical structures of adenine, guanine, and 2-aminopurine.

Article Snippet: Finally, to screen for potential inhibitors of the M. tuberculosis DnaE1 exonuclease we used a nucleotide compound library from MedChemExpress that contains ∼200 nucleotide and nucleoside analogues.

Techniques: Fluorescence, Comparison